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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
20.3
Human Site:
Y227
Identified Species:
40.61
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
Y227
S
G
L
V
W
R
G
Y
R
R
P
L
R
P
K
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
F96
H
Q
Y
F
H
I
C
F
V
S
G
M
R
I
K
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
D196
Q
P
P
F
F
P
E
D
P
Q
Q
S
N
A
C
Dog
Lupus familis
XP_547113
1504
165780
Y227
S
G
L
V
W
R
G
Y
R
R
L
L
G
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
Y233
S
G
L
L
W
R
G
Y
K
K
L
L
G
P
K
Rat
Rattus norvegicus
O88269
1502
164977
Y233
S
G
L
L
W
K
G
Y
R
K
L
L
G
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
Y244
T
G
L
M
V
Q
G
Y
K
R
P
L
E
A
S
Chicken
Gallus gallus
Q5F364
1525
170953
H232
T
G
L
M
I
Q
G
H
R
R
P
L
E
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
Y232
T
G
L
M
V
K
G
Y
K
R
P
L
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
M139
V
I
S
A
L
T
V
M
I
L
T
P
T
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
S228
T
G
V
V
V
T
T
S
N
V
T
A
P
A
K
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
M226
S
R
I
T
F
S
W
M
S
G
L
M
K
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
0
80
N.A.
66.6
66.6
N.A.
46.6
53.3
N.A.
53.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
13.3
86.6
N.A.
86.6
86.6
N.A.
73.3
80
N.A.
80
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
9
0
34
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
25
9
9
% E
% Phe:
0
0
0
17
17
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
0
67
0
0
0
0
59
0
0
9
9
0
25
0
9
% G
% His:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
9
9
0
0
9
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
17
0
0
25
17
0
0
9
0
59
% K
% Leu:
0
0
59
17
9
0
0
0
0
9
34
59
0
0
0
% L
% Met:
0
0
0
25
0
0
0
17
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
9
9
0
0
9
0
0
9
0
34
9
9
34
0
% P
% Gln:
9
9
0
0
0
17
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
9
0
0
0
25
0
0
34
42
0
0
17
0
0
% R
% Ser:
42
0
9
0
0
9
0
9
9
9
0
9
0
0
9
% S
% Thr:
34
0
0
9
0
17
9
0
0
0
17
0
9
17
0
% T
% Val:
9
0
9
25
25
0
9
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
34
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _